![]() , that various phytochemicals modify ex vivo γδ-T cell proliferation. We have shown in human consumption studies with an encapsulated dried fruit and vegetable juice fraction These studies suggest that systemic immunity is modified by the bioactive compounds in cranberries, but have not directly assessed it.Īn immune cell particularly suited to surveillance of the genitourinary tract is the γδ-T cell, which is strategically located in the epithelium of both the intestine and the reproductive tract. , but did not examine the influence on systemic immunity. Recent clinical interventions with cranberry have focused on pyuria and bacteriuria Recent studies have shown effectiveness of cranberry in reducing reoccurrence of urinary tract infections and an enhanced generation of anti-lymphoma antibodies was detected in an immuno-competent mouse model of lymphoma lower levels of urinary IL-6 were found in pregnant women after drinking cranberry juice for at least 3 days consumption of a cranberry beverage in a human intervention study resulted in a reduction in pathogen in 42% of the subjects without altering normal vaginal microbiota rather than modification of immune function.įour studies have shown the effects of cranberry on immune function in diverse ways: in a rabbit model of infection-induced oxidative renal damage, cranberry reduced inflammation However, although the responsibility of immune cells is to survey their environment and prevent bacterial and viral infections from overwhelming the body, much of the literature regarding cranberry research has focused on adherence of bacteria Cranberries and cranberry juice are associated with promoting urinary tract health
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